Frontiers The Effect Of Growth Hormone On Ovarian Function Recovery Therefore, the effects of gh and the mechanisms by which it promotes ovarian function recovery need to be evaluated. the present study was designed with the aim of evaluating the effects and mechanisms of the action of gh on ovarian function recovery in ovarian insufficiency (oi) induced by the administration of cp in a mouse model. Liu et al. showed that gh promotes ovarian tissue repair, estrogen release, and oocyte maturation via activation of the notch 1 signaling pathway in a mouse model (17). yigiter et al. found that gh reduced ovarian tissue damage in a rat model; this may be attributed to the antioxidant properties of gh (18).
Frontiers The Effect Of Growth Hormone On Ovarian Function Recovery Objectives: to evaluate the effects and mechanisms of action of growth hormone (gh) in the recovery of ovarian function in ovarian insufficiency induced by cyclophosphamide (cp) in a mouse model. materials and methods: after inducing ovarian insufficiency by administering 400 mg kg of cp intraperitoneally to 6 week old icr mice, the mice were. Ovarian gh would act in an autocrine paracrine way, so the hormone could play a role in the regulation of ovarian angiogenesis, as suggested by the fact that ovarian expression of the gh gene increases during follicular development (11), but significantly decreases when immature follicles reinitiated meiosis (111). Objectives to evaluate the effects and mechanisms of action of growth hormone (gh) in the recovery of ovarian function in ovarian insufficiency induced by cyclophosphamide (cp) in a mouse model. The effect of growth hormone on ovarian function recovery in a mouse model of ovarian insufficiency. kim, su mi; yoo, jung young; hong, yeon hee et al. in: frontiers in endocrinology, vol. 14, 1184977, 2023. research output: contribution to journal › article › peer review.
Frontiers The Effect Of Growth Hormone On Ovarian Function Recovery Objectives to evaluate the effects and mechanisms of action of growth hormone (gh) in the recovery of ovarian function in ovarian insufficiency induced by cyclophosphamide (cp) in a mouse model. The effect of growth hormone on ovarian function recovery in a mouse model of ovarian insufficiency. kim, su mi; yoo, jung young; hong, yeon hee et al. in: frontiers in endocrinology, vol. 14, 1184977, 2023. research output: contribution to journal › article › peer review. Gh treatment may promote the recovery of ovarian function in ovarian insufficiency induced by the administration of cp via decreasing apoptosis and stromal fibrosis and upregulating lep, pecam 1, and ang genes. objectives to evaluate the effects and mechanisms of action of growth hormone (gh) in the recovery of ovarian function in ovarian insufficiency induced by cyclophosphamide (cp) in a. Although most of the gh effects on the ovarian function are exerted by the hormone locally produced in the ovaries, systemic gh released by the pituitary gland or exogenously administered, also.
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