Nucleotide How the hydrolytic activity of mitochondrial ATP synthase is modulated during brown adipose tissue (BAT) thermogenesis remains unexplored This study demonstrates that reduction of inhibitory factor 1 FAO is catalyzed by the mitochondrial trifunctional protein (MTP) and, if overloaded, generates ROS ROS are boosted during stressful events, favoring cardiac maladaptive remodeling Melusin is a
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